Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells
5-Fluorouracil (5-FU) is commonly used for the therapy of colon cancer; however, acquired resistance to 5-FU is a critical barrier to successful treatment and the primary cause of chemotherapy failure. Epithelialmesenchymal transition (EMT) is a process whereby cells undergo alterations in morpholog...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Korean Society Of Toxicology
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505345/ |