The detection of EpCAM+ and EpCAM– circulating tumor cells

EpCAM expressing circulating tumor cells, detected by CellSearch, are predictive of short survival in several cancers and may serve as a liquid biopsy to guide therapy. Here we investigate the presence of EpCAM+ CTC detected by CellSearch and EpCAM– CTC discarded by CellSearch, after EpCAM based enr...

Full description

Bibliographic Details
Main Authors: Wit, Sanne de, Dalum, Guus van, Lenferink, Aufried T. M., Tibbe, Arjan G. J., Hiltermann, T. Jeroen N., Groen, Harry J. M., van Rijn, Cees J. M., Terstappen, Leon W. M. M.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505332/