EpCAM proteolysis: new fragments with distinct functions?
EpCAM [epithelial cell adhesion molecule; CD326 (cluster of differentiation 326)] is highly expressed on epithelium-derived tumours and can play a role in cell proliferation. Recently, RIP (regulated intramembrane proteolysis) has been implicated as the trigger for EpCAM-mediated proliferative signa...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2013
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601740/ |