Interleukin (IL)-21 promotes intestinal IgA response to microbiota

Commensal microbiota-specific Th17 cells are enriched in the intestines, which can convert into Tfh in Peyer’s patches, and are crucial for production of intestinal IgA against microbiota, however, the role of Th17 and Tfh cytokines in regulating the mucosal IgA response to enteric microbiota is sti...

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Bibliographic Details
Main Authors: Cao, Anthony T., Yao, Suxia, Gong, Bin, Nurieva, Roza I., Elson, Charles O., Cong, Yingzi
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501922/