Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells

Freshly isolated murine PP B cells were cultured with 10 different cytokines, including IL-1 alpha, IL-2, IL-4, IL-5, IL-6, IL-7, IFN- gamma, TNF-alpha, and TGF-beta, to investigate a possible role for these cytokines in induction of Ig synthesis. Of interest was the finding that only IL-5 and both...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1989
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189333/