Assessing Dissimilarity Measures for Sample-Based Hierarchical Clustering of RNA Sequencing Data Using Plasmode Datasets
Sample- and gene- based hierarchical cluster analyses have been widely adopted as tools for exploring gene expression data in high-throughput experiments. Gene expression values (read counts) generated by RNA sequencing technology (RNA-seq) are discrete variables with special statistical properties,...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498680/ |