Lack of inhibitory effects of the anti-fibrotic drug imatinib on endothelial cell functions in vitro and in vivo

Systemic sclerosis (SSc) is a systemic autoimmune disease that is characterized by microangiopathy with progressive loss of capillaries and tissue fibrosis. Imatinib exerts potent anti-fibrotic effects and is currently evaluated in clinical trials. The aim of the present study was to exclude that th...

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Bibliographic Details
Main Authors: Venalis, Paulius, Maurer, Britta, Akhmetshina, Alfiya, Busch, Nicole, Dees, Clara, Stürzl, Michael, Zwerina, Jochen, Jüngel, Astrid, Gay, Steffen, Schett, Georg, Distler, Oliver, Distler, Jörg HW
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496125/