Platelet-derived serotonin links vascular disease and tissue fibrosis

Blocking 5-HT2B receptor provides a therapeutic target for fibrotic diseases caused by activated platelet release of serotonin during vascular damage.

Bibliographic Details
Main Authors: Dees, Clara, Akhmetshina, Alfiya, Zerr, Pawel, Reich, Nicole, Palumbo, Katrin, Horn, Angelika, Jüngel, Astrid, Beyer, Christian, Krönke, Gerhard, Zwerina, Jochen, Reiter, Rudolf, Alenina, Natalia, Maroteaux, Luc, Gay, Steffen, Schett, Georg, Distler, Oliver, Distler, Jörg H.W.
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092343/