Osteopontin as two-sided mediator of intestinal inflammation
Osteopontin (OPN) is characterized as a major amplifier of Th1-immune responses. However, its role in intestinal inflammation is currently unknown. We found considerably raised OPN levels in blood of wild-type (WT) mice with dextran sodium sulfate (DSS)-induced colitis. To identify the role of this...
Main Authors: | Heilmann, Katja, Hoffmann, Ute, Witte, Ellen, Loddenkemper, Christoph, Sina, Christian, Schreiber, Stefan, Hayford, Claudia, Holzlbhner, Pamela, Wolk, Kerstin, Tchatchou, Elianne, Moos, Verena, Zeitz, Martin, Sabat, Robert, Giinthert, Ursula, Wittig, Bianca Maria |
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Format: | Online |
Language: | English |
Published: |
John Wiley & Sons, Ltd
2009
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496111/ |
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