Osteopontin as two-sided mediator of intestinal inflammation

Osteopontin as two-sided mediator of intestinal inflammation

Osteopontin (OPN) is characterized as a major amplifier of Th1-immune responses. However, its role in intestinal inflammation is currently unknown. We found considerably raised OPN levels in blood of wild-type (WT) mice with dextran sodium sulfate (DSS)-induced colitis. To identify the role of this...

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Bibliographic Details
Main Authors: Heilmann, Katja, Hoffmann, Ute, Witte, Ellen, Loddenkemper, Christoph, Sina, Christian, Schreiber, Stefan, Hayford, Claudia, Holzlbhner, Pamela, Wolk, Kerstin, Tchatchou, Elianne, Moos, Verena, Zeitz, Martin, Sabat, Robert, Giinthert, Ursula, Wittig, Bianca Maria
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496111/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496111/

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