Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

Schwann cells degrade myelin after injury by a novel form of selective autophagy, myelinophagy, which is positively regulated by the JNK/c-Jun pathway and is defective in the injured central nervous system.

Bibliographic Details
Main Authors:	Gomez-Sanchez, Jose A., Carty, Lucy, Iruarrizaga-Lejarreta, Marta, Palomo-Irigoyen, Marta, Varela-Rey, Marta, Griffith, Megan, Hantke, Janina, Macias-Camara, Nuria, Azkargorta, Mikel, Aurrekoetxea, Igor, De Juan, Virginia Gutiérrez, Jefferies, Harold B.J., Aspichueta, Patricia, Elortza, Félix, Aransay, Ana M., Martínez-Chantar, María L., Baas, Frank, Mato, José M., Mirsky, Rhona, Woodhoo, Ashwin, Jessen, Kristján R.
Format:	Online
Language:	English
Published:	The Rockefeller University Press 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494002/

id	pubmed-4494002
recordtype	oai_dc
spelling	pubmed-44940022016-01-06 Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves Gomez-Sanchez, Jose A. Carty, Lucy Iruarrizaga-Lejarreta, Marta Palomo-Irigoyen, Marta Varela-Rey, Marta Griffith, Megan Hantke, Janina Macias-Camara, Nuria Azkargorta, Mikel Aurrekoetxea, Igor De Juan, Virginia Gutiérrez Jefferies, Harold B.J. Aspichueta, Patricia Elortza, Félix Aransay, Ana M. Martínez-Chantar, María L. Baas, Frank Mato, José M. Mirsky, Rhona Woodhoo, Ashwin Jessen, Kristján R. Research Articles Schwann cells degrade myelin after injury by a novel form of selective autophagy, myelinophagy, which is positively regulated by the JNK/c-Jun pathway and is defective in the injured central nervous system. The Rockefeller University Press 2015-07-06 /pmc/articles/PMC4494002/ /pubmed/26150392 http://dx.doi.org/10.1083/jcb.201503019 Text en © 2015 Gomez-Sanchez et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Gomez-Sanchez, Jose A. Carty, Lucy Iruarrizaga-Lejarreta, Marta Palomo-Irigoyen, Marta Varela-Rey, Marta Griffith, Megan Hantke, Janina Macias-Camara, Nuria Azkargorta, Mikel Aurrekoetxea, Igor De Juan, Virginia Gutiérrez Jefferies, Harold B.J. Aspichueta, Patricia Elortza, Félix Aransay, Ana M. Martínez-Chantar, María L. Baas, Frank Mato, José M. Mirsky, Rhona Woodhoo, Ashwin Jessen, Kristján R.
spellingShingle	Gomez-Sanchez, Jose A. Carty, Lucy Iruarrizaga-Lejarreta, Marta Palomo-Irigoyen, Marta Varela-Rey, Marta Griffith, Megan Hantke, Janina Macias-Camara, Nuria Azkargorta, Mikel Aurrekoetxea, Igor De Juan, Virginia Gutiérrez Jefferies, Harold B.J. Aspichueta, Patricia Elortza, Félix Aransay, Ana M. Martínez-Chantar, María L. Baas, Frank Mato, José M. Mirsky, Rhona Woodhoo, Ashwin Jessen, Kristján R. Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
author_facet	Gomez-Sanchez, Jose A. Carty, Lucy Iruarrizaga-Lejarreta, Marta Palomo-Irigoyen, Marta Varela-Rey, Marta Griffith, Megan Hantke, Janina Macias-Camara, Nuria Azkargorta, Mikel Aurrekoetxea, Igor De Juan, Virginia Gutiérrez Jefferies, Harold B.J. Aspichueta, Patricia Elortza, Félix Aransay, Ana M. Martínez-Chantar, María L. Baas, Frank Mato, José M. Mirsky, Rhona Woodhoo, Ashwin Jessen, Kristján R.
author_sort	Gomez-Sanchez, Jose A.
title	Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
title_short	Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
title_full	Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
title_fullStr	Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
title_full_unstemmed	Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
title_sort	schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
description	Schwann cells degrade myelin after injury by a novel form of selective autophagy, myelinophagy, which is positively regulated by the JNK/c-Jun pathway and is defective in the injured central nervous system.
publisher	The Rockefeller University Press
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494002/
_version_	1613244894754635776

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

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