c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration. c-Jun governs major aspects of the injury response, determines...

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Bibliographic Details
Main Authors: Arthur-Farraj, Peter J., Latouche, Morwena, Wilton, Daniel K., Quintes, Susanne, Chabrol, Elodie, Banerjee, Ambily, Woodhoo, Ashwin, Jenkins, Billy, Rahman, Mary, Turmaine, Mark, Wicher, Grzegorz K., Mitter, Richard, Greensmith, Linda, Behrens, Axel, Raivich, Gennadij, Mirsky, Rhona, Jessen, Kristján R.
Format: Online
Language:English
Published: Cell Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657176/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657176/

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