Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly

Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly

In eukaryotes, RNA Polymerase III (Pol III) is specifically responsible for transcribing genes encoding tRNAs and other short non-coding RNAs. The recruitment of Pol III to tRNA-encoding genes requires the transcription factors (TF) IIIB and IIIC. TFIIIC has been described as a conserved, multi-subu...

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Bibliographic Details
Main Authors: Male, Gary, von Appen, Alexander, Glatt, Sebastian, Taylor, Nicholas M. I., Cristovao, Michele, Groetsch, Helga, Beck, Martin, Müller, Christoph W.
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490372/

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