Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

Major depressive disorder (MDD) and obesity are frequently co-morbid and this correlation is partly due to genetic factors. Although specific genetic risk variants are associated with body mass index (BMI) and with larger effect sizes in depressed individuals, the genetic overlap and interaction wit...

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Bibliographic Details
Main Authors: Clarke, T-K, Hall, L S, Fernandez-Pujals, A M, MacIntyre, D J, Thomson, P, Hayward, C, Smith, B H, Padmanabhan, S, Hocking, L J, Deary, I J, Porteous, D J, McIntosh, A M
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490293/

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