Expression of pancreatic and duodenal homeobox1 (PDX1) protein in the interior and exterior regions of the intestine, revealed by development and analysis of Pdx1 knockout mice
We developed pancreatic and duodenal homeobox1 (Pdx1) knockout mice to improve a compensatory hyperinsulinemia, which was induced by hyperplasia in the β cells or Langerhans' islands, as the diabetic model mice. For targeting of Pdx1 gene by homologous recombination, ES cells derived from a 129...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Association for Laboratory Animal Science
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490151/ |