Binding Polymorphism in the DNA Bound State of the Pdx1 Homeodomain

The subtle effects of DNA-protein recognition are illustrated in the homeodomain fold. This is one of several small DNA binding motifs that, in spite of limited DNA binding specificity, adopts crucial, specific roles when incorporated in a transcription factor. The homeodomain is composed of a 3-hel...

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Bibliographic Details
Main Authors: Babin, Volodymyr, Wang, Dongli, Rose, Robert B., Sagui, Celeste
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738460/