Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers

Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers

Somatic mutations in the nuclear genome are required for tumor formation, but the functional consequences of somatic mitochondrial DNA (mtDNA) mutations are less understood. Here we identify somatic mtDNA mutations across 527 tumors and 14 cancer types, using an approach that takes advantage of evid...

Full description

Bibliographic Details
Main Authors: Stewart, James B., Alaei-Mahabadi, Babak, Sabarinathan, Radhakrishnan, Samuelsson, Tore, Gorodkin, Jan, Gustafsson, Claes M., Larsson, Erik
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488357/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488357/

Similar Items