RNAsnp: Efficient Detection of Local RNA Secondary Structure Changes Induced by SNPs

Structural characteristics are essential for the functioning of many noncoding RNAs and cis-regulatory elements of mRNAs. SNPs may disrupt these structures, interfere with their molecular function, and hence cause a phenotypic effect. RNA folding algorithms can provide detailed insights into structu...

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Bibliographic Details
Main Authors: Sabarinathan, Radhakrishnan, Tafer, Hakim, Seemann, Stefan E, Hofacker, Ivo L, Stadler, Peter F, Gorodkin, Jan
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708107/