Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche
Communication between stem and niche supporting cells maintains the homeostasis of adult tissues. Wnt signaling is a crucial regulator of the stem cell niche, but the mechanism that governs Wnt ligand delivery in this compartment has not been fully investigated. We identified that Wnt secretion is p...
Main Authors: | Das, Soumyashree, Yu, Shiyan, Sakamori, Ryotaro, Vedula, Pavan, Feng, Qiang, Flores, Juan, Hoffman, Andrew, Fu, Jiang, Stypulkowski, Ewa, Rodriguez, Alexis, Dobrowolski, Radek, Harada, Akihiro, Hsu, Wei, Bonder, Edward M., Verzi, Michael P., Gao, Nan |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483769/ |
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