Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth

Early B cell development is orchestrated by the combined activities of the transcriptional regulators E2A, EBF1, Foxo1 and Ikaros. However, how the genome-wide binding patterns of these regulators are modulated during B-lineage development remains to be determined. Here, we found that in lymphoid pr...

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Bibliographic Details
Main Authors: Bossen, Claudia, Murre, Caroline S, Chang, Aaron N, Mansson, Robert, Rodewald, Hans-Reimer, Murre, Cornelis
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474778/