Global changes in nuclear positioning of genes and intra- and inter-domain genomic interactions that orchestrate B cell fate

The genome is folded into domains located in either transcriptionally inert or permissive compartments. Here we used genome-wide strategies to characterize domains during B cell development. Structured Interaction Matrix Analysis revealed that CTCF occupancy was primarily associated with intra-domai...

Full description

Bibliographic Details
Main Authors: Lin, Yin C, Benner, Christopher, Mansson, Robert, Heinz, Sven, Miyazaki, Kazuko, Miyazaki, Masaki, Chandra, Vivek, Bossen, Claudia, Glass, Christopher K, Murre, Cornelis
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501570/