Global changes in nuclear positioning of genes and intra- and inter-domain genomic interactions that orchestrate B cell fate
The genome is folded into domains located in either transcriptionally inert or permissive compartments. Here we used genome-wide strategies to characterize domains during B cell development. Structured Interaction Matrix Analysis revealed that CTCF occupancy was primarily associated with intra-domai...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501570/ |