2-methoxyestradiol Prevents LNCaP Tumor Development in Nude Mice: Potential Role of G2/M Regulatory Proteins

Nontoxic naturally occurring metabolite of estrogen namely 2-methoxyestradial (2ME2) found in serum and urine has been shown to be antitumorigenic in various tumor models including the prostate. A recent study conducted in breast cancer cells showed growth stimulatory effect of 2ME2 when used at low...

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Bibliographic Details
Main Authors: Horny, Cara, Balasubashini, Muralimanoharan Sri, Komanduri, Krishna, Ganapathy, Manonmani, Yeh, I-Tien, Ghosh, Rita, Kumar, Addanki P.
Format: Online
Language:English
Published: Libertas Academica 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474335/