Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease

The nitroheterocyclic drugs nifurtimox and benznidazole are first-line drugs available to treat Chagas disease; however, they have limitations, including long treatment courses and toxicity. Strategies to overcome these limitations include the identification of new drugs with specific target profile...

Full description

Bibliographic Details
Main Authors: Assíria Fontes Martins, Tassiane, de Figueiredo Diniz, Lívia, Mazzeti, Ana Lia, da Silva do Nascimento, Álvaro Fernando, Caldas, Sérgio, Caldas, Ivo Santana, de Andrade, Isabel Mayer, Ribeiro, Isabela, Bahia, Maria Terezinha
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468053/