Benznidazole-resistance in Trypanosoma cruzi: Evidence that distinct mechanisms can act in concert☆
Clones isolated from a single benznidazole-resistant Trypanosoma cruzi population contain a stop-codon-generating mutation in the nitroreductase gene TcNTR. Clonal variation in resistance suggests that additional mechanisms must also operate.
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier/North-Holland Biomedical Press
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988956/ |