Split-alignment of genomes finds orthologies more accurately
We present a new pair-wise genome alignment method, based on a simple concept of finding an optimal set of local alignments. It gains accuracy by not masking repeats, and by using a statistical model to quantify the (un)ambiguity of each alignment part. Compared to previous animal genome alignments,...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464727/ |