Improved search heuristics find 20 000 new alignments between human and mouse genomes

Sequence similarity search is a fundamental way of analyzing nucleotide sequences. Despite decades of research, this is not a solved problem because there exist many similarities that are not found by current methods. Search methods are typically based on a seed-and-extend approach, which has many v...

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Bibliographic Details
Main Authors: Frith, Martin C., Noé, Laurent
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985675/