G-protein-coupled receptor 30-mediated antiapoptotic effect of estrogen on spinal motor neurons following injury and its underlying mechanisms

Spinal cord injury (SCI) may result in severe dysfunction of motor neurons. G-protein-coupled receptor 30 (GPR30) expression in the motor neurons of the ventral horn of the spinal cord mediates neuroprotection through estrogen signaling. The present study explored the antiapoptotic effect of estroge...

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Bibliographic Details
Main Authors: CHEN, JINGYU, HU, RONG, GE, HONGFEI, DUANMU, WANGSHENG, LI, YUHONG, XUE, XINGSENG, HU, SHENGLI, FENG, HUA
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464192/