The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock☆
The mitochondria-shaping protein optic atrophy 1 (OPA1) has genetically distinguishable roles in mitochondrial morphology and apoptosis. The latter depends on the presenilin associated rhomboid like (PARL) protease, essential for the accumulation of a soluble intermembrane space form of OPA1 (IMS-OP...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Pub. Co
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686154/ |