Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer

Colorectal cancer (CRC) is one of the most common and fatal malignancies worldwide. The poor prognosis of colorectal cancer patients is due to development of chemoresistance and cancer metastasis. Recently osteopontin (OPN) has been associated with stem-like properties in colorectal cancer. This stu...

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Bibliographic Details
Main Authors: Ng, Lui, Wan, Timothy, Chow, Ariel, Iyer, Deepak, Man, Johnny, Chen, Guanghua, Yau, Thomas Chung-Cheung, Lo, Oswens, Foo, Chi-Chung, Poon, Jensen Tung-Chung, Poon, Ronnie Tung-Ping, Pang, Roberta, Law, Wai-Lun
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461767/