A Novel Lung Explant Model for the Ex Vivo Study of Efficacy and Mechanisms of Anti-Influenza Drugs

Influenza A virus causes considerable morbidity and mortality largely because of a lack of effective antiviral drugs. Viral neuraminidase inhibitors, which inhibit viral release from the infected cell, are currently the only approved drugs for influenza, but have recently been shown to be less effec...

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Bibliographic Details
Main Authors: Nicholas, Ben, Staples, Karl J., Moese, Stefan, Meldrum, Eric, Ward, Jon, Dennison, Patrick, Havelock, Tom, Hinks, Timothy S. C., Amer, Khalid, Woo, Edwin, Chamberlain, Martin, Singh, Neeta, North, Malcolm, Pink, Sandy, Wilkinson, Tom M. A., Djukanović, Ratko
Format: Online
Language:English
Published: AAI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456633/