Vorinostat enhances chemosensitivity to arsenic trioxide in K562 cell line

Objective. This study aimed to investigate the chemosensitive augmentation effect and mechanism of HDAC inhibitor Vorinostat (SAHA) in combination with arsenic trioxide (ATO) on proliferation and apoptosis of K562 cells.

Bibliographic Details
Main Authors: Li, Nainong, Guan, Xiaoyan, Li, Fang, Li, Xiaofan, Chen, Yuanzhong
Format: Online
Language:English
Published: PeerJ Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451029/