Tetramethylpyrazine potentiates arsenic trioxide activity against HL-60 cell lines

The objective of this study was to evaluate the effects of tetramethylpyrazine (TMP) in combination with arsenic trioxide (As2O3) on the proliferation and differentiation of HL-60 cells. The HL-60 cells were treated with 300 µg/mL TMP, 0.5 µM As2O3, and 300 µg/mL TMP combined with 0.5 µM As2O3, resp...

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Bibliographic Details
Main Authors: Wu, Yuni, Xu, Youhua, Shen, Yali, Wang, Cuicui, Guo, Gaili, Hu, Tiantian
Format: Online
Language:English
Published: Sociedade Brasileira de Medicina Tropical 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854191/