The Hill analysis and co-ion–driven transporter kinetics

Interaction of multiple ligands with a protein or protein complex is a widespread phenomenon that allows for cooperativity. Here, we review the use of the Hill equation, which is commonly used to analyze binding or kinetic data, to analyze the kinetics of ion-coupled transporters and show how the me...

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Bibliographic Details
Main Authors: Lolkema, Juke S., Slotboom, Dirk-Jan
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442790/