Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia

Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia

The adapter protein metastasis suppressor 1 (MTSS1) is implicated as a tumor suppressor or tumor promoter, depending on the type of solid cancer. Here, we identified Mtss1 expression to be increased in AML subsets with favorable outcome, while suppressed in high risk AML patients. High expression of...

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Bibliographic Details
Main Authors: Schemionek, Mirle, Kharabi Masouleh, Behzad, Klaile, Yvonne, Krug, Utz, Hebestreit, Katja, Schubert, Claudia, Dugas, Martin, Büchner, Thomas, Wörmann, Bernhard, Hiddemann, Wolfgang, Berdel, Wolfgang E., Brümmendorf, Tim H., Müller-Tidow, Carsten, Koschmieder, Steffen
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440712/

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