MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture
The conserved MICOS complex functions as a primary determinant of mitochondrial inner membrane structure. We address the organization and functional roles of MICOS and identify two independent MICOS subcomplexes: Mic27/Mic10/Mic12, whose assembly is dependent on respiratory complexes and the mitocho...
Main Authors: | Friedman, Jonathan R, Mourier, Arnaud, Yamada, Justin, McCaffery, J Michael, Nunnari, Jodi |
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Format: | Online |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434539/ |
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