MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

The conserved MICOS complex functions as a primary determinant of mitochondrial inner membrane structure. We address the organization and functional roles of MICOS and identify two independent MICOS subcomplexes: Mic27/Mic10/Mic12, whose assembly is dependent on respiratory complexes and the mitocho...

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Bibliographic Details
Main Authors: Friedman, Jonathan R, Mourier, Arnaud, Yamada, Justin, McCaffery, J Michael, Nunnari, Jodi
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434539/