Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis

Mycobacterial tuberculosis (Mtb) is able to preserve its intrabacterial pH (pHIB) near neutrality in the acidic phagosomes of immunologically activated macrophages and to cause lethal pathology in immunocompetent mice. In contrast, when its ability to maintain pHIB homeostasis is genetically compro...

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Bibliographic Details
Main Authors: Zhao, Nan, Sun, Mingna, Burns-Huang, Kristin, Jiang, Xiuju, Ling, Yan, Darby, Crystal, Ehrt, Sabine, Liu, Gang, Nathan, Carl
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433263/