Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis

Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis

Bacterial pathogens like Mycobacterium tuberculosis (Mtb) encounter acidic microenvironments in the host and must maintain their acid-base homeostasis to survive. A genetic screen identified two Mtb strains that cannot control intrabacterial pH (pHIB) in an acidic environment; infection with either...

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Bibliographic Details
Main Authors: Darby, Crystal M., Ingólfsson, Helgi I., Jiang, Xiuju, Shen, Chun, Sun, Mingna, Zhao, Nan, Burns, Kristin, Liu, Gang, Ehrt, Sabine, Warren, J. David, Anderson, Olaf S., Brickner, Steven J., Nathan, Carl
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728290/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728290/

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