Diacylglycerol O-Acyltransferase Type-1 Synthesizes Retinyl Esters in the Retina and Retinal Pigment Epithelium

Retinyl esters represent an insoluble storage form of vitamin A and are substrates for the retinoid isomerase (Rpe65) in cells of the retinal pigment epithelium (RPE). The major retinyl-ester synthase in RPE cells is lecithin:retinol acyl-transferase (LRAT). A second palmitoyl coenzyme A-dependent r...

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Bibliographic Details
Main Authors: Kaylor, Joanna J., Radu, Roxana A., Bischoff, Nicholas, Makshanoff, Jacob, Hu, Jane, Lloyd, Marcia, Eddington, Shannan, Bianconi, Tran, Bok, Dean, Travis, Gabriel H.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431840/