Interleukin-1 as an Injury Signal Mobilizes Retinyl Esters in Hepatic Stellate Cells through Down Regulation of Lecithin Retinol Acyltransferase

Retinoids are mostly stored as retinyl esters in hepatic stellate cells (HSCs) through esterification of retinol and fatty acid, catalyzed by lecithin-retinol acyltransferase (LRAT). This study is designated to address how retinyl esters are mobilized in liver injury for tissue repair and wound heal...

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Main Authors: Kida, Yujiro, Xia, Zanxian, Zheng, Sujun, Mordwinkin, Nicholas M., Louie, Stan G., Zheng, Song Guo, Feng, Min, Shi, Hongbo, Duan, Zhongping, Han, Yuan-Ping
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208544/