Eprobe-mediated screening system for somatic mutations in the KRAS locus
Activating mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) loci are largely predictive of resistance to epidermal growth factor receptor (EGFR) therapy in colorectal cancer (CRC). A highly sensitive detection system for the KRAS gene mutations is urgently needed; however, conventi...
Main Authors: | ATSUMI, JUN, HANAMI, TAKESHI, ENOKIDA, YASUAKI, OGAWA, HIROOMI, DELOBEL, DIANE, MITANI, YASUMASA, KIMURA, YASUMASA, SOMA, TAKAHIRO, TAGAMI, MICHIHIRA, TAKASE, YOSHIAKI, ICHIHARA, TATSUO, TAKEYOSHI, IZUMI, USUI, KENGO, HAYASHIZAKI, YOSHIHIDE, SHIMIZU, KIMIHIRO |
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Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431451/ |
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