Eprobe-mediated screening system for somatic mutations in the KRAS locus

Activating mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) loci are largely predictive of resistance to epidermal growth factor receptor (EGFR) therapy in colorectal cancer (CRC). A highly sensitive detection system for the KRAS gene mutations is urgently needed; however, conventi...

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Main Authors: ATSUMI, JUN, HANAMI, TAKESHI, ENOKIDA, YASUAKI, OGAWA, HIROOMI, DELOBEL, DIANE, MITANI, YASUMASA, KIMURA, YASUMASA, SOMA, TAKAHIRO, TAGAMI, MICHIHIRA, TAKASE, YOSHIAKI, ICHIHARA, TATSUO, TAKEYOSHI, IZUMI, USUI, KENGO, HAYASHIZAKI, YOSHIHIDE, SHIMIZU, KIMIHIRO
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431451/