Spindle assembly checkpoint is sufficient for complete Cdc20 sequestering in mitotic control
The spindle checkpoint assembly (SAC) ensures genome fidelity by temporarily delaying anaphase onset, until all chromosomes are properly attached to the mitotic spindle. The SAC delays mitotic progression by preventing activation of the ubiquitin ligase anaphase-promoting complex (APC/C) or cyclosom...
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| Format: | Online |
| Language: | English |
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Research Network of Computational and Structural Biotechnology
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430708/ |