Kinetochore–microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint

The spindle assembly checkpoint (SAC) is a genome surveillance mechanism that protects against aneuploidization. Despite profound progress on understanding mechanisms of its activation, it remains unknown what aspect of chromosome–spindle interactions is monitored by the SAC: kinetochore–microtubule...

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Bibliographic Details
Main Authors: Etemad, Banafsheh, Kuijt, Timo E. F., Kops, Geert J. P. L.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686852/