Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling

Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling

We identified a novel Akt signaling mechanism that mediates fucoidan-induced suppression of human colon cancer cell (HT29) proliferation and anticancer effects. Fucoidan treatment significantly inhibited growth, induced G1-phase-associated upregulation of p21WAF1 expression, and suppressed cyclin an...

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Bibliographic Details
Main Authors:	Han, Yong-seok, Lee, Jun Hee, Lee, Sang Hun
Format:	Online
Language:	English
Published:	The Korean Society of Applied Pharmacology 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428714/

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