Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling
We identified a novel Akt signaling mechanism that mediates fucoidan-induced suppression of human colon cancer cell (HT29) proliferation and anticancer effects. Fucoidan treatment significantly inhibited growth, induced G1-phase-associated upregulation of p21WAF1 expression, and suppressed cyclin an...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Society of Applied Pharmacology
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428714/ |