John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y Receptors☆

John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y Receptors☆

We establish structure activity relationships of extracellular nucleosides and nucleotides at G protein-coupled receptors (GPCRs), e.g. adenosine receptors (ARs) and P2Y receptors (P2YRs), respectively. We synthesize selective agents for use as pharmacological probes and potential therapeutic agents...

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Bibliographic Details
Main Authors: Jacobson, Kenneth A., Gao, Zhan-Guo, Paoletta, Silvia, Kiselev, Evgeny, Chakraborty, Saibal, Jayasekara, P. Suresh, Balasubramanian, Ramachandran, Tosh, Dilip K.
Format: Online
Language:English
Published: Research Network of Computational and Structural Biotechnology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423517/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423517/

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