Exceptional longevity and muscle and fitness related genotypes: a functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795, and ACSL1 rs6552828

Exceptional longevity and muscle and fitness related genotypes: a functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795, and ACSL1 rs6552828

There are several gene variants that are candidates to influence functional capacity in long-lived individuals. As such, their potential association with exceptional longevity (EL, i.e., reaching 100+ years) deserves analysis. Among them are rs7832552 in the thyrotropin-releasing hormone receptor (T...

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Bibliographic Details
Main Authors: Fuku, Noriyuki, He, Zi-hong, Sanchis-Gomar, Fabian, Pareja-Galeano, Helios, Tian, Ye, Arai, Yasumichi, Abe, Yukiko, Murakami, Haruka, Miyachi, Motohiko, Zempo, Hirofumi, Naito, Hisashi, Yvert, Thomas, Verde, Zoraida, Venturini, Letizia, Fiuza-Luces, Carmen, Santos-Lozano, Alejandro, Rodriguez-Romo, Gabriel, Ricevuti, Giovanni, Hirose, Nobuyoshi, Emanuele, Enzo, Garatachea, Nuria, Lucia, Alejandro
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422078/

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