Impact of Acute Malaria on Pre-Existing Antibodies to Viral and Vaccine Antigens in Mice and Humans

Impact of Acute Malaria on Pre-Existing Antibodies to Viral and Vaccine Antigens in Mice and Humans

Vaccine-induced immunity depends on long-lived plasma cells (LLPCs) that maintain antibody levels. A recent mouse study showed that Plasmodium chaubaudi infection reduced pre-existing influenza-specific antibodies—raising concerns that malaria may compromise pre-existing vaccine responses. We extend...

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Bibliographic Details
Main Authors: Banga, Simran, Coursen, Jill D., Portugal, Silvia, Tran, Tuan M., Hancox, Lisa, Ongoiba, Aissata, Traore, Boubacar, Doumbo, Ogobara K., Huang, Chiung-Yu, Harty, John T., Crompton, Peter D.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412709/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412709/

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