Exposure-Dependent Control of Malaria-Induced Inflammation in Children

In malaria-naïve individuals, Plasmodium falciparum infection results in high levels of parasite-infected red blood cells (iRBCs) that trigger systemic inflammation and fever. Conversely, individuals in endemic areas who are repeatedly infected are often asymptomatic and have low levels of iRBCs, ev...

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Bibliographic Details
Main Authors: Portugal, Silvia, Moebius, Jacqueline, Skinner, Jeff, Doumbo, Safiatou, Doumtabe, Didier, Kone, Younoussou, Dia, Seydou, Kanakabandi, Kishore, Sturdevant, Daniel E., Virtaneva, Kimmo, Porcella, Stephen F., Li, Shanping, Doumbo, Ogobara K., Kayentao, Kassoum, Ongoiba, Aissata, Traore, Boubacar, Crompton, Peter D.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990727/